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A platform for continuously growing biomedical knowledge

The Biomedical Intelligence® Cloud was designed from the ground up to enable learning and growing knowledge from heterogeneous biomedical data and literature.

Biomedical Intelligence Cloud

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Key Platform Components

Data Hub – Semantic Data Integration

A semantic data integration and management system that unifies public and private data into a harmonized, searchable repository enriched with detailed metadata.

  • Unified Repository: Combines multi-omics, clinical, and literature data in one platform.
  • Deep Annotations: Enhances data searchability with semantic metadata.
  • Collaboration-Ready: Supports secure data sharing across teams and projects.
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Biomedical App Engine – AI-Powered Analysis Tools

A suite of powerful bioinformatics and machine learning apps designed to extract actionable insights from complex biomedical data.

  • Comprehensive Tools: Over 12 apps to analyze your data, including pathway and single-cell analyses, predictive modeling and more.
  • NLP Engine: Extract insights from literature, clinical trials and patents.
  • Knowledge Graph Integration: Leverage the CURIE Knowledge Graph for enriched, context-aware analysis.
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CURIE Knowledge Graph – Knowledge Synthesis at Scale

A continuously updated, data- and literature-driven knowledge graph that synthesizes biomedical knowledge to power discovery.

  • Comprehensive Knowledge: Over 4 billion data and literature relations connecting genes, diseases, drugs and other biomedical entities.
  • Multi-Dimensional Insights: Enables 360° exploration of biomedical entities with evidence from multiple data types.
  • Dynamic Updates: Continuously integrates new data and literature.
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AI Solutions

Purpose-built foundation models and AI-powered tools that drive discoveries and deliver context-rich, explainable insights.

  • Predictive Insights: Identify complex biomarkers and response patterns.
  • Context-Rich Analysis: Combine structured data and literature for robust findings.
  • Interactive Reports: Generate explainable, traceable summaries and scientific narratives.
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Biomedical App Engine

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Pathway Expression Analysis

  • Identify key pathways for your condition of interest
  • Over 20 pathway domains included
  • CURIE Knowledge Graph integration for contextual analysis and interpretation
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Single Cell Analysis

  • Analyze and interactively explore single-cell and spatial transcriptomics data
  • Identify cell clusters, annotate cell types, and visualize the results
  • Identify cell-type-specific markers, correlate with outcomes, integrate with CURIE Knowledge Graph
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Multi-Dimensional Cohort Analysis

  • Identify multidimensional omics and clinical predictors of clinical and phenotypic outcomes
  • Model covariates, interactions and random effects
  • Analyze categoric, continuous, survival and temporal data
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Disease Subtyping

  • Identify molecular subtypes of disease based on multidimensional omics data
  • Automatically assign new samples into subtypes
  • Associate subtypes with molecular and clinical outcomes
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Cell Type Deconvolution

  • Identify and quantify up to 64 cell types represented in bulk mRNA data
  • Correlate cell types with clinical outcomes and other metadata
  • Expand your analysis to additional cell types using custom gene signatures.
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Predictive Modeling

  • Supervised learning trained on clinical or molecular outcomes
  • Interpretable machine learning models
  • Identify optimal and biologically-meaningful predictive feature combinations
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CURIE Data Evidence Matrix

  • Data-driven context-specific associations linking genes, pathways, diseases, drugs, and other biomedical entities.
  • Hierarchically organized multidimensional evidence
  • Continuously updated based on new data and data analyses.
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CURIE Literature Evidence

  • Literature evidence extracted from scientific abstracts, publications, clinical trial descriptions and patents
  • Explore co-occurence, semantic similarity and direct sentence-level relations
  • LLM-based natural language processing and semantic relation classification engine
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Multi-Entity View

  • Interrogate associations between multiple CURIE entities simultaneously
  • Explore gene signatures across diseases or compare responses to multiple drugs
  • Hierarchically organized multidimensional evidence
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Network Analysis

  • Go from tables to networks to gain functional, systems-level understanding
  • Interrogate disease, drug treatment, response and/or resistance
  • Understand underlying mechanisms
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Omics Insights

  • Interactively explore cohorts with multi-omics and clinical data
  • Interrogate single gene markers and/or gene signatures
  • Test associations between omics and clinical measurements and outcomes
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Gene Profile Search and Analysis

  • Search gene profiles from millions of analyses
  • Discover conditions and contexts with profiles matching your query
  • Interrogate profile similarities and differences using the Analysis Comparison App

Powered by the CURIE Knowledge Graph

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Samples 58,555,948

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Entities 1,091,114

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Analyses 3,277,134

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Relations 4,187,567,805

Data4Cure vs Other platforms

 

Biomedical Intelligence Cloud

Reach Out Today for a Platform Demo

Other Platforms



Typical scenario representative of most other platforms in the field

Comprehensive Data Integration and Harmonization
Included
Integrates multi-omics, clinical, and literature data into a unified repository with deep semantic annotations.
Limited
Many platforms focus on specific data types (e.g., genomics-only, single-cell-only or clinical data-only), leading to fragmented workflows.
Support for Public and Private Data
Included
Natively supports both public and privite datasets with data ingestion and harmonization tools.
Varied
Many platforms focus on either public or private data.
Comrehensive Suite of Data Analysis Apps
Included
A Biomedical App Engine with 12+ Apps for pathway analysis, disease subtyping, single-cell analysis, and predictive modeling.
Limited
Many platform offer only a limited set of tools requiring manual data export/import between applications, disrupting workflows.
Ability to Continuously Update Knowledge from Data
Included
Multiple Apps seamlessly share results across workflows and contribute to the CURIE Knowledge Graph for continuous learning and contextual analysis of new data.
None or Limited
Analytics platforms typically do not feature a knowledge graph or include a static knowledge graph that is not continuously informed by new data.
Data and Literature Knowledge
Included
Data4Cure's CURIE Knowledge Graph natively integrates knowledge from data and literature.
Limited
Most platforms and knowledge graphs focus on either liteature- or data-driven knowledge
Advanced Contextual and Integrative Analysis
Included
When researchers analyze a new dataset, the The CURIE Knowledge Graph places findings in the context of thousands of prior studies, highlighting shared connections between genes, diseases, biomarkers, treatments, and outcomes.
None or Limited
Most analytics platforms focus on analyzing individual datasets or offer less powerful comparative analysis capabilities.

Data4Cure vs Custom development

 

Biomedical Intelligence Cloud

Reach Out Today for a Platform Demo

In-House Solution


Using custom pipelines and applications or combining multiple third-party solutions

Rapid Deployment and Scalability
Get Started in Days
Offers a ready-to-use platform with pre-built tools, apps, and integrations that can be quickly implemented. Scales seamlessly to handle large volumes of multi-omics, clinical, and literature data.
Years to Implement
Requires significant time and resources for development, testing, optimization, ongoing maintenance and scaling.
Comprehensive Semantic Data Integration
Included
Integrate and harmonize datasets using semantic ontologies and deep metadata annotations. Provides support for complex multi-modal data, such as genomics, transcriptomics, proteomics and clinical trial data.
Challenging
Requires development and updates of custom ontologies, creation of data pipelines and ontology mapping tools and continuous curation and update of public datasets.
Continuous Data Updates
Included
Provides continuous updates from public databases, literature, and user-uploaded data.
Challenging
Requires manual data updates and validation processes, increasing the risk of outdated insights.
Maintenance & Operational Cost
Included
Included with our subscription plans.
Significant
Estimated in millions of dollars per year in engineering, infrascructure and data science costs
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